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Structure and Dynamics of the Myristoyl Lipid Modification of Src Peptides Determined by (2)H Solid-State NMR Spectroscopy

Lipid modifications of proteins are widespread in nature and play an important role in numerous biological processes. The nonreceptor tyrosine kinase Src is equipped with an N-terminal myristoyl chain and a cluster of basic amino acids for the stable membrane association of the protein. We used (2)H...

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Detalhes bibliográficos
Main Authors: Scheidt, Holger A., Huster, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711427/
https://ncbi.nlm.nih.gov/pubmed/19413971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.02.028
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