Structural changes at microtubule ends accompanying GTP hydrolysis: Information from a slowly hydrolyzable analogue of GTP, guanylyl (α,β)methylenediphosphonate

Microtubules are dynamic polymers that interconvert between periods of slow growth and fast shrinkage. The energy driving this nonequilibrium behavior comes from the hydrolysis of GTP, which is required to destabilize the microtubule lattice. To understand the mechanism of this destabilization, cryo...

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-д хэвлэсэн:	Proc Natl Acad Sci U S A
Үндсэн зохиолчид:	Müller-Reichert, Thomas, Chrétien, Denis, Severin, Fedor, Hyman, Anthony A.
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	National Academy of Sciences 1998
Нөхцлүүд:	Biological Sciences
Онлайн хандалт:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19892/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9520422/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.7.3661
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