Wird geladen...

Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells

Cdc6 has a critical regulatory role in the initiation of DNA replication in yeasts, but its function in mammalian cells has not been characterized. We show here that Cdc6 is expressed selectively in proliferating but not quiescent mammalian cells, both in culture and within tissues of intact animals...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Yan, Zhen, DeGregori, James, Shohet, Ralph, Leone, Gustavo, Stillman, Bruce, Nevins, Joseph R., Williams, R. Sanders
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC19882/
https://ncbi.nlm.nih.gov/pubmed/9520412
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!