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Total Synthesis of (+)-Asperazine

The first total synthesis of the structurally novel cyclotryptophan alkaloid asperazine is reported. The central step in the synthetic sequence is a diastereoselective intramolecular Heck reaction in which the substituent controlling stereoselection is external to the ring being formed. This synthes...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Govek, Steven P., Overman, Larry E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1987397/
https://ncbi.nlm.nih.gov/pubmed/11562240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2007.05.127
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