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Cyclin box structure of the P-TEFb subunit Cyclin T1 derived from a fusion complex with EIAV Tat
The positive transcription elongation factor b (P-TEFb) is an essential regulator of viral gene expression during the life cycle of HIV-1. Its Cyclin T1 subunit forms a ternary complex with the viral Tat protein and the TAR RNA element thereby activating cyclin dependent kinase 9 (Cdk9), which stimu...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1987359/ https://ncbi.nlm.nih.gov/pubmed/17540406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.04.077 |
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