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Cyclin box structure of the P-TEFb subunit Cyclin T1 derived from a fusion complex with EIAV Tat

The positive transcription elongation factor b (P-TEFb) is an essential regulator of viral gene expression during the life cycle of HIV-1. Its Cyclin T1 subunit forms a ternary complex with the viral Tat protein and the TAR RNA element thereby activating cyclin dependent kinase 9 (Cdk9), which stimu...

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Main Authors: Anand, Kanchan, Schulte, Antje, Fujinaga, Koh, Scheffzek, Klaus, Geyer, Matthias
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1987359/
https://ncbi.nlm.nih.gov/pubmed/17540406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.04.077
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