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In vivo interaction of prostacyclin with an inhibitor of cyclic nucleotide phosphodiesterase, HL 725.

Prostacyclin (PGI2) inactivates platelets by stimulation of adenylate cyclase, and its effect can be potentiated in vitro by simultaneous inhibition of cyclic AMP phosphodiesterase. The interaction of synthetic PGI2 and the potent phosphodiesterase inhibitor HL 725 was studied in a model of systemic...

詳細記述

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書誌詳細
主要な著者: Darius, H., Lefer, A. M., Leprán, I., Smith, J. B.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 1985
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1987149/
https://ncbi.nlm.nih.gov/pubmed/2985163
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