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CD8+ T Cells Directed Against a Viral Peptide Contribute to Loss of Motor Function by Disrupting Axonal Transport in a Viral Model of Fulminant Demyelination

Demyelination, a pathological hallmark of multiple sclerosis, may be a necessary but not a sufficient condition for motor dysfunction associated with this disease. We favor a neurodegenerative model of multiple sclerosis and suggest that demyelination creates a permissive environment wherein the den...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Howe, Charles L., Ure, Daren, Adelson, Jaimie A., LaFrance-Corey, Reghann, Rodriguez, Moses
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986839/
https://ncbi.nlm.nih.gov/pubmed/17493690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2007.04.005
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