Quantitative Ultrastructural Analysis of a Single Spinal Cord Demyelinated Lesion Predicts Total Lesion Load, Axonal Loss, and Neurological Dysfunction in a Murine Model of Multiple Sclerosis

Infection of susceptible mice with Theiler’s murine encephalomyelitis virus results in neurological dysfunction from progressive central nervous system demyelination that is pathologically similar to the human disease, multiple sclerosis. We hypothesized that the development of neuropathology procee...

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Main Authors: Sathornsumetee, Sith, McGavern, Dorian B., Ure, Daren R., Rodriguez, Moses
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2000
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850158/
https://ncbi.nlm.nih.gov/pubmed/11021839
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