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Absence of perforin expression confers axonal protection despite demyelination

Current evidence suggests that demyelination may be a necessary but not a sufficient condition for neurologic deficits associated with multiple sclerosis. Axon injury that occurs within the permissive environment of the demyelinated lesion is better correlated with functional deficits, but the mecha...

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Detalhes bibliográficos
Main Authors: Howe, Charles L., Adelson, Jaimie D., Rodriguez, Moses
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1857307/
https://ncbi.nlm.nih.gov/pubmed/17112732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2006.10.001
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