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Robust protein–protein interactions in crowded cellular environments

The capacity of proteins to interact specifically with one another underlies our conceptual understanding of how living systems function. Systems-level study of specificity in protein–protein interactions is complicated by the fact that the cellular environment is crowded and heterogeneous; interact...

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Autori principali: Deeds, Eric J., Ashenberg, Orr, Gerardin, Jaline, Shakhnovich, Eugene I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986594/
https://ncbi.nlm.nih.gov/pubmed/17848524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702766104
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