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Transcriptional regulation of the thyrotropin-releasing hormone gene by leptin and melanocortin signaling

Starvation causes a rapid reduction in thyroid hormone levels in rodents. This adaptive response is caused by a reduction in thyrotropin-releasing hormone (TRH) expression that can be reversed by the administration of leptin. Here we examined hypothalamic signaling pathways engaged by leptin to upre...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Harris, Mark, Aschkenasi, Carl, Elias, Carol F., Chandrankunnel, Annie, Nillni, Eduardo A., Bjørbæk, Christian, Elmquist, Joel K., Flier, Jeffrey S., Hollenberg, Anthony N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC198547/
https://ncbi.nlm.nih.gov/pubmed/11134186
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