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Crystal structure of the catalytic domain of human tumor necrosis factor-α-converting enzyme

Tumor necrosis factor-α (TNFα) is a cytokine that induces protective inflammatory reactions and kills tumor cells but also causes severe damage when produced in excess, as in rheumatoid arthritis and septic shock. Soluble TNFα is released from its membrane-bound precursor by a membrane-anchored prot...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Maskos, Klaus, Fernandez-Catalan, Carlos, Huber, Robert, Bourenkov, Gleb P., Bartunik, Hans, Ellestad, George A., Reddy, Pranitha, Wolfson, Martin F., Rauch, Charles T., Castner, Beverly J., Davis, Raymond, Clarke, Howard R. G., Petersen, Melissa, Fitzner, Jeffrey N., Cerretti, Douglas Pat, March, Carl J., Paxton, Raymond J., Black, Roy A., Bode, Wolfram
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1998
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19849/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9520379/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.7.3408
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