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Co-expression of the neuronal α(7) and L247T α(7) mutant subunits yields hybrid nicotinic receptors with properties of both wild-type α(7) and α(7) mutant homomeric receptors

Injection of cDNA encoding the neuronal α(7) subunit into Xenopus oocytes yields homomeric receptors showing responses to AcCho that have low affinity, fast desensitization, nonlinear current–voltage (I–V) relation, and sensitivity to α-bungarotoxin (α-BTX) and 5-hydroxytryptamine (5HT), both substa...

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Sonraí bibleagrafaíochta
Foilsithe in:Proc Natl Acad Sci U S A
Príomhchruthaitheoirí: Palma, E., Eusebi, F., Miledi, R.
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: National Academy of Sciences 1997
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19827/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9037089/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.4.1539
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