Co-expression of the neuronal α(7) and L247T α(7) mutant subunits yields hybrid nicotinic receptors with properties of both wild-type α(7) and α(7) mutant homomeric receptors
Injection of cDNA encoding the neuronal α(7) subunit into Xenopus oocytes yields homomeric receptors showing responses to AcCho that have low affinity, fast desensitization, nonlinear current–voltage (I–V) relation, and sensitivity to α-bungarotoxin (α-BTX) and 5-hydroxytryptamine (5HT), both substa...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19827/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9037089/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.4.1539 |
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