Persistent expression of human clotting factor IX from mouse liver after intravenous injection of adeno-associated virus vectors
We previously found that gene transduction by adeno-associated virus (AAV) vectors in cell culture can be stimulated over 100-fold by treatment of the target cells with agents that affect DNA metabolism, such as irradiation or topoisomerase inhibitors. Here we show that previous γ-irradiation increa...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1997
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19807/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9037069/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.4.1426 |
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