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MVB-12, a Fourth Subunit of Metazoan ESCRT-I, Functions in Receptor Downregulation

After ligand binding and endocytosis, cell surface receptors can continue to signal from endosomal compartments until sequestered from the cytoplasm. An important mechanism for receptor downregulation in vivo is via the inward budding of receptors into intralumenal vesicles to form specialized endos...

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Bibliografski detalji
Glavni autori: Audhya, Anjon, McLeod, Ian X., Yates, John R., Oegema, Karen
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978536/
https://ncbi.nlm.nih.gov/pubmed/17895996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000956
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