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MVB-12, a Fourth Subunit of Metazoan ESCRT-I, Functions in Receptor Downregulation

After ligand binding and endocytosis, cell surface receptors can continue to signal from endosomal compartments until sequestered from the cytoplasm. An important mechanism for receptor downregulation in vivo is via the inward budding of receptors into intralumenal vesicles to form specialized endos...

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Detalles Bibliográficos
Main Authors: Audhya, Anjon, McLeod, Ian X., Yates, John R., Oegema, Karen
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978536/
https://ncbi.nlm.nih.gov/pubmed/17895996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000956
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