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Induction of neostriatal neurogenesis slows disease progression in a transgenic murine model of Huntington disease
Ependymal overexpression of brain-derived neurotrophic factor (BDNF) stimulates neuronal addition to the adult striatum, from subependymal progenitor cells. Noggin, by suppressing subependymal gliogenesis and increasing progenitor availability, potentiates this process. We asked whether BDNF/Noggin...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1978427/ https://ncbi.nlm.nih.gov/pubmed/17885687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31778 |
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