IL-13Rα2 and IL-10 coordinately suppress airway inflammation, airway-hyperreactivity, and fibrosis in mice

Development of persistent Th2 responses in asthma and chronic helminth infections are a major health concern. IL-10 has been identified as a critical regulator of Th2 immunity, but mechanisms for controlling Th2 effector function remain unclear. IL-10 also has paradoxical effects on Th2-associated p...

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Autores principales: Wilson, Mark S., Elnekave, Eldad, Mentink-Kane, Margaret M., Hodges, Marcus G., Pesce, John T., Ramalingam, Thirumalai R., Thompson, Robert W., Kamanaka, Masahito, Flavell, Richard A., Keane-Myers, Andrea, Cheever, Allen W., Wynn, Thomas A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2007
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978425/
https://ncbi.nlm.nih.gov/pubmed/17885690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31546
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