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MECHANISTIC PATHWAYS AND BIOLOGICAL ROLES FOR RECEPTOR-INDEPENDENT ACTIVATORS OF G-PROTEIN SIGNALING

Signal processing via heterotrimeric G-proteins in response to cell surface receptors is a central and much investigated aspect of how cells integrate cellular stimuli to produce coordinated biological responses. The system is a target of numerous therapeutic agents, plays an important role in adapt...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Blumer, Joe B., Smrcka, Alan V., Lanier, S.M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978177/
https://ncbi.nlm.nih.gov/pubmed/17240454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2006.11.001
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