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Overexpression, purification and crystallization of an archaeal DNA ligase from Pyrococcus furiosus
DNA ligases seal single-strand breaks in double-stranded DNA and their function is essential to maintain the integrity of the genome during various aspects of DNA metabolism, such as replication, excision repair and recombination. DNA-strand breaks are frequently generated as reaction intermediates...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
International Union of Crystallography
2005
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1978145/ https://ncbi.nlm.nih.gov/pubmed/16511246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309105038649 |
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