Chargement en cours...

RNA editing of the microRNA-151 precursor blocks cleavage by the Dicer–TRBP complex

MicroRNAs (miRNAs) mediate translational repression or degradation of their target messenger RNAs by RNA interference (RNAi). The primary transcripts of miRNA genes (pri-miRNAs) are sequentially processed by the nuclear Drosha–DGCR8 complex to approximately 60–70 nucleotide (nt) intermediates (pre-m...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Kawahara, Yukio, Zinshteyn, Boris, Chendrimada, Thimmaiah P, Shiekhattar, Ramin, Nishikura, Kazuko
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978079/
https://ncbi.nlm.nih.gov/pubmed/17599088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401011
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!