The relationships between glutathione, glutathione-S-transferase and cytotoxicity of platinum drugs and melphalan in eight human ovarian carcinoma cell lines.

The role of glutathione (GSH) and GSH-S-transferase (GST) activity in modulating the cytotoxicity of four platinum drugs and melphalan was evaluated in eight human ovarian carcinoma cell lines. The cell lines were established from solid and ascitic tumours from pretreated and untreated patients, and...

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Bibliographic Details
Main Authors: Mistry, P., Kelland, L. R., Abel, G., Sidhar, S., Harrap, K. R.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1991
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977519/
https://ncbi.nlm.nih.gov/pubmed/1892748
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