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Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4

The peptide hormone hepcidin is the principal regulator of systemic iron homeostasis. We examined the pathway by which iron stimulates the production of hepcidin. In humans who ingested 65 mg of iron, the increase in transferrin saturation preceded by hours the increase in urinary hepcidin excretion...

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Bibliografski detalji
Glavni autori: Lin, Lan, Valore, Erika V., Nemeth, Elizabeta, Goodnough, Julia B., Gabayan, Victoria, Ganz, Tomas
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976373/
https://ncbi.nlm.nih.gov/pubmed/17540841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-04-087593
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