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Soluble hemojuvelin is released by proprotein convertase-mediated cleavage at a conserved polybasic RNRR site
As the principal iron-regulatory hormone, hepcidin plays an important role in systemic iron homeostasis. The regulation of hepcidin expression by iron loading appears to be unexpectedly complex and has attracted much interest. The GPI-linked membrane protein hemojuvelin (GPI-hemojuvelin) is an essen...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2211380/ https://ncbi.nlm.nih.gov/pubmed/17869549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2007.06.023 |
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