Platelet activation in patients with sickle disease, hemolysis-associated pulmonary hypertension, and nitric oxide scavenging by cell-free hemoglobin

Increased platelet activation is recognized in patients with sickle cell disease (SCD), but its pathogenesis and clinical relevance remain uncertain. Pulmonary arterial hypertension (PAH), an important complication of SCD, is characterized by a proliferative pulmonary vasculopathy, in situ thrombosi...

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Bibliografiska uppgifter
Huvudupphovsmän: Villagra, José, Shiva, Sruti, Hunter, Lori A., Machado, Roberto F., Gladwin, Mark T., Kato, Gregory J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2007
Ämnen:
Red Cells
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976348/
https://ncbi.nlm.nih.gov/pubmed/17536019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-12-061697
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