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Topoisomerase V relaxes supercoiled DNA by a constrained swiveling mechanism

Topoisomerase V is a type I topoisomerase without structural or sequence similarities to other topoisomerases. Although it belongs to the type I subfamily of topoisomerases, it is unrelated to either type IA or IB enzymes. We used real-time single-molecule micromechanical experiments to show that to...

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Bibliografische gegevens
Hoofdauteurs: Taneja, Bhupesh, Schnurr, Bernhard, Slesarev, Alexei, Marko, John F., Mondragón, Alfonso
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976220/
https://ncbi.nlm.nih.gov/pubmed/17804808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701989104
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