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Configuration-dependent diffusion can shift the kinetic transition state and barrier height of protein folding
We show that diffusion can play an important role in protein-folding kinetics. We explicitly calculate the diffusion coefficient of protein folding in a lattice model. We found that diffusion typically is configuration- or reaction coordinate-dependent. The diffusion coefficient is found to be decre...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1976201/ https://ncbi.nlm.nih.gov/pubmed/17804812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606506104 |
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