Rapid determination of single base mismatch mutations in DNA hybrids by direct electric field control
We have demonstrated that controlled electric fields can be used to regulate transport, concentration, hybridization, and denaturation of single- and double-stranded oligonucleotides. Discrimination among oligonucleotide hybrids with widely varying binding strengths may be attained by simple adjustm...
Spremljeno u:
| Izdano u: | Proc Natl Acad Sci U S A |
|---|---|
| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1997
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19754/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9037016/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.4.1119 |
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