Rapid determination of single base mismatch mutations in DNA hybrids by direct electric field control

We have demonstrated that controlled electric fields can be used to regulate transport, concentration, hybridization, and denaturation of single- and double-stranded oligonucleotides. Discrimination among oligonucleotide hybrids with widely varying binding strengths may be attained by simple adjustm...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Sosnowski, Ronald G., Tu, Eugene, Butler, William F., O’Connell, James P., Heller, Michael J.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1997
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19754/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9037016/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.4.1119
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