Rapid determination of single base mismatch mutations in DNA hybrids by direct electric field control

We have demonstrated that controlled electric fields can be used to regulate transport, concentration, hybridization, and denaturation of single- and double-stranded oligonucleotides. Discrimination among oligonucleotide hybrids with widely varying binding strengths may be attained by simple adjustm...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Sosnowski, Ronald G., Tu, Eugene, Butler, William F., O’Connell, James P., Heller, Michael J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19754/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9037016/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.4.1119
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!