Rapid determination of single base mismatch mutations in DNA hybrids by direct electric field control

We have demonstrated that controlled electric fields can be used to regulate transport, concentration, hybridization, and denaturation of single- and double-stranded oligonucleotides. Discrimination among oligonucleotide hybrids with widely varying binding strengths may be attained by simple adjustm...

Disgrifiad llawn

Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Proc Natl Acad Sci U S A
Prif Awduron:	Sosnowski, Ronald G., Tu, Eugene, Butler, William F., O’Connell, James P., Heller, Michael J.
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	National Academy of Sciences 1997
Pynciau:	Biological Sciences
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19754/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9037016/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.4.1119
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!