A role of unliganded thyroid hormone receptor in postembryonic development in Xenopus laevis

A fascinating feature of thyroid hormone (T3) receptors (TR) is that they constitutively bind to promoter regions of T3-response genes, providing dual functions. In the presence of T3, TR activates T3-inducible genes, while unliganded TR represses these same genes. Although this dual function model...

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Bibliographic Details
Main Authors: Sato, Yukiyasu, Buchholz, Daniel R., Paul, Bindu D., Shi, Yun-Bo
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1973152/
https://ncbi.nlm.nih.gov/pubmed/17482434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2007.03.006
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