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Unliganded thyroid hormone receptor is essential for Xenopus laevis eye development

Thyroid hormone receptors generally activate transcription of target genes in the presence of thyroid hormone (T(3)) and repress their transcription in its absence. Here, we investigated the role of unliganded thyroid hormone receptor (TR) during vertebrate development using an amphibian model. Prev...

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Detalhes bibliográficos
Main Authors: Havis, Emmanuelle, Le Mevel, Sébastien, Morvan Dubois, Ghislaine, Shi, De-Li, Scanlan, Thomas S, Demeneix, Barbara A, Sachs, Laurent M
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618110/
https://ncbi.nlm.nih.gov/pubmed/17006540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601356
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