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Unliganded thyroid hormone receptor is essential for Xenopus laevis eye development

Thyroid hormone receptors generally activate transcription of target genes in the presence of thyroid hormone (T(3)) and repress their transcription in its absence. Here, we investigated the role of unliganded thyroid hormone receptor (TR) during vertebrate development using an amphibian model. Prev...

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Autors principals: Havis, Emmanuelle, Le Mevel, Sébastien, Morvan Dubois, Ghislaine, Shi, De-Li, Scanlan, Thomas S, Demeneix, Barbara A, Sachs, Laurent M
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618110/
https://ncbi.nlm.nih.gov/pubmed/17006540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601356
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