Immunogenicity of virus-like particles containing modified human immunodeficiency virus envelope proteins

Extensive glycosylation and variable loops of the HIV envelope protein (Env) are reported to shield some neutralizing epitopes. Here, we investigated the immunogenicity of mutated HIV Envs presented in virus-like particles (VLPs). We immunized mice with simian human immunodeficiency virus (SHIV) VLP...

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Main Authors: Quan, Fu-Shi, Sailaja, Gangadhara, Skountzou, Ioanna, Huang, Chunzi, Vzorov, Andrei, Compans, Richard W., Kang, Sang-Moo
格式: Artigo
語言:Inglês
出版: 2007
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1973151/
https://ncbi.nlm.nih.gov/pubmed/17320250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.01.107
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