Incorporation of Glycosylphosphatidylinositol-Anchored Granulocyte- Macrophage Colony-Stimulating Factor or CD40 Ligand Enhances Immunogenicity of Chimeric Simian Immunodeficiency Virus-Like Particles

The rapid worldwide spread of human immunodeficiency virus (HIV) mandates the development of successful vaccination strategies. Since live attenuated HIV is not accepted as a vaccine due to safety concerns, virus-like particles (VLPs) offer an attractive safe alternative because they lack the viral...

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Auteurs principaux: Skountzou, Ioanna, Quan, Fu-Shi, Gangadhara, Sailaja, Ye, Ling, Vzorov, Andrei, Selvaraj, Periasamy, Jacob, Joshy, Compans, Richard W., Kang, Sang-Moo
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2007
Sujets:
Vaccines and Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797543/
https://ncbi.nlm.nih.gov/pubmed/17108046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01692-06
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