Immunogenicity of virus-like particles containing modified human immunodeficiency virus envelope proteins

Extensive glycosylation and variable loops of the HIV envelope protein (Env) are reported to shield some neutralizing epitopes. Here, we investigated the immunogenicity of mutated HIV Envs presented in virus-like particles (VLPs). We immunized mice with simian human immunodeficiency virus (SHIV) VLP...

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Detalhes bibliográficos
Main Authors: Quan, Fu-Shi, Sailaja, Gangadhara, Skountzou, Ioanna, Huang, Chunzi, Vzorov, Andrei, Compans, Richard W., Kang, Sang-Moo
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1973151/
https://ncbi.nlm.nih.gov/pubmed/17320250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.01.107
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