Immunogenicity of virus-like particles containing modified human immunodeficiency virus envelope proteins

Extensive glycosylation and variable loops of the HIV envelope protein (Env) are reported to shield some neutralizing epitopes. Here, we investigated the immunogenicity of mutated HIV Envs presented in virus-like particles (VLPs). We immunized mice with simian human immunodeficiency virus (SHIV) VLP...

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Hlavní autoři: Quan, Fu-Shi, Sailaja, Gangadhara, Skountzou, Ioanna, Huang, Chunzi, Vzorov, Andrei, Compans, Richard W., Kang, Sang-Moo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1973151/
https://ncbi.nlm.nih.gov/pubmed/17320250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.01.107
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