Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase

Hyperhomocyst(e)inemia is a metabolic derangement that is linked to the distribution of folate pools, which provide one-carbon units for biosynthesis of purines and thymidylate and for remethylation of homocysteine to form methionine. In humans, methionine synthase deficiency results in the accumula...

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Main Authors: Elmore, C. Lee, Wu, Xuchu, Leclerc, Daniel, Watson, Erica D., Bottiglieri, Teodoro, Krupenko, Natalia I., Krupenko, Sergey A., Cross, James C., Rozen, Rima, Gravel, Roy A., Matthews, Rowena G.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1973089/
https://ncbi.nlm.nih.gov/pubmed/17369066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2007.02.001
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