Sequential WT1 and CTNNB1 mutations and alterations of β‐catenin localisation in intralobar nephrogenic rests and associated Wilms tumours: two case studies

BACKGROUND: Intralobar nephrogenic rests (ILNRs) are precursor lesions for Wilms tumours and are associated with WT1 gene mutations. ILNR‐associated Wilms tumours have a co‐clustering of WT1 and β‐catenin (CTNNB1) mutations and unique histological features characterised by a stromal‐predominant hist...

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Hlavní autoři: Fukuzawa, Ryuji, Heathcott, Rosemary W, More, Helen E, Reeve, Anthony E
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Group 2007
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1972432/
https://ncbi.nlm.nih.gov/pubmed/17172473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.2006.043083
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