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Domain V of 23S rRNA contains all the structural elements necessary for recognition by the ErmE methyltransferase.

The ErmE methyltransferase from the erythromycin-producing actinomycete Saccharopolyspora erythraea dimethylates the N-6 position of adenine 2058 in domain V of 23S rRNA. This modification confers resistance to erythromycin and to other macrolide, lincosamide, and streptogramin B antibiotics. We inv...

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Detaylı Bibliyografya
Yayımlandı:J Bacteriol
Asıl Yazarlar: Vester, B, Douthwaite, S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 1994
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC197073/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7961464/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.22.6999-7004.1994
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