Domain V of 23S rRNA contains all the structural elements necessary for recognition by the ErmE methyltransferase.
The ErmE methyltransferase from the erythromycin-producing actinomycete Saccharopolyspora erythraea dimethylates the N-6 position of adenine 2058 in domain V of 23S rRNA. This modification confers resistance to erythromycin and to other macrolide, lincosamide, and streptogramin B antibiotics. We inv...
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| Опубликовано в:: | J Bacteriol |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology (ASM)
1994
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC197073/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7961464/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.22.6999-7004.1994 |
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