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A dually active anthrax vaccine that confers protection against both bacilli and toxins

Systemic anthrax is caused by unimpeded bacillar replication and toxin secretion. We developed a dually active anthrax vaccine (DAAV) that confers simultaneous protection against both bacilli and toxins. DAAV was constructed by conjugating capsular poly-γ-d-glutamic acid (PGA) to protective antigen...

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Autors principals: Rhie, Gi-Eun, Roehrl, Michael H., Mourez, Michael, Collier, R. John, Mekalanos, John J., Wang, Julia Y.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC196904/
https://ncbi.nlm.nih.gov/pubmed/12960361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1834478100
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