Genetic regulation of telomere-telomere fusions in the yeast Saccharomyces cerevisae
Yeast strains with mutations in both TEL1 and MEC1 have short telomeres and elevated rates of chromosome deletions. By using a PCR assay, we demonstrate that mec1 tel1 strains also have telomere–telomere fusions (T-TFs). T-TFs require Lig4p (a ligase required for nonhomologous end-joining DNA repair...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2003
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196892/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12963812/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1934561100 |
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