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Genetic regulation of telomere-telomere fusions in the yeast Saccharomyces cerevisae
Yeast strains with mutations in both TEL1 and MEC1 have short telomeres and elevated rates of chromosome deletions. By using a PCR assay, we demonstrate that mec1 tel1 strains also have telomere–telomere fusions (T-TFs). T-TFs require Lig4p (a ligase required for nonhomologous end-joining DNA repair...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC196892/ https://ncbi.nlm.nih.gov/pubmed/12963812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1934561100 |
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