Gene mutations and increased levels of p53 protein in human squamous cell carcinomas and their cell lines.

Using immunocytochemical and Western blotting techniques we have demonstrated the presence of abnormally high levels of p53 protein in 8/24 (33%) of human squamous cell carcinomas (SCC) and 9/18 (50%) of SCC cell lines. There was a correlation between the immunocytochemical results obtained with eig...

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Hauptverfasser: Burns, J. E., Baird, M. C., Clark, L. J., Burns, P. A., Edington, K., Chapman, C., Mitchell, R., Robertson, G., Soutar, D., Parkinson, E. K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1993
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968513/
https://ncbi.nlm.nih.gov/pubmed/8390283
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