Gene mutations and increased levels of p53 protein in human squamous cell carcinomas and their cell lines.

Using immunocytochemical and Western blotting techniques we have demonstrated the presence of abnormally high levels of p53 protein in 8/24 (33%) of human squamous cell carcinomas (SCC) and 9/18 (50%) of SCC cell lines. There was a correlation between the immunocytochemical results obtained with eig...

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Autors principals: Burns, J. E., Baird, M. C., Clark, L. J., Burns, P. A., Edington, K., Chapman, C., Mitchell, R., Robertson, G., Soutar, D., Parkinson, E. K.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1993
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968513/
https://ncbi.nlm.nih.gov/pubmed/8390283
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