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Transplantation of wild-type white adipose tissue normalizes metabolic, immune and inflammatory alterations in leptin-deficient ob/ob mice
Leptin-deficient ob/ob mice exhibit several metabolic and immune abnormalities, including thymus atrophy and markedly reduced inflammatory responses. We evaluated whether transplantation of wild type (WT) white adipose tissue (WAT) into ob/ob mice could mimic the effect of recombinant leptin adminis...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1968154/ https://ncbi.nlm.nih.gov/pubmed/17368040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2007.02.001 |
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