Role of leptin receptor-induced STAT3 signaling in modulation of intestinal and hepatic inflammation in mice

Leptin-deficient ob/ob mice are resistant to dextran sulfate sodium (DSS)-induced colitis and Concanavalin A (Con A)-induced hepatitis. However, the signal transduction pathways involved have not been identified. The present study investigated the effect of leptin-induced STAT3 signaling in the DSS...

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Detalhes bibliográficos
Main Authors: Gove, Melissa E., Rhodes, Davina H., Pini, Maria, van Baal, Jantine W., Sennello, Joseph A., Fayad, Raja, Cabay, Robert J., Myers, Martin G., Fantuzzi, Giamila
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Leukocyte Biology 2009
Assuntos:
Receptors, Signal Transduction, and Genes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653948/
https://ncbi.nlm.nih.gov/pubmed/19052144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0808508
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