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Transplantation of wild-type white adipose tissue normalizes metabolic, immune and inflammatory alterations in leptin-deficient ob/ob mice

Leptin-deficient ob/ob mice exhibit several metabolic and immune abnormalities, including thymus atrophy and markedly reduced inflammatory responses. We evaluated whether transplantation of wild type (WT) white adipose tissue (WAT) into ob/ob mice could mimic the effect of recombinant leptin adminis...

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Detalhes bibliográficos
Main Authors: Sennello, Joseph A., Fayad, Raja, Pini, Maria, Gove, Melissa E., Fantuzzi, Giamila
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968154/
https://ncbi.nlm.nih.gov/pubmed/17368040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2007.02.001
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