Bcl-2 expression causes redistribution of glutathione to the nucleus

In this study we used HeLa cells transfected with a conditional Bcl-2 expression construct to study the effects of Bcl-2 on reduced glutathione (GSH) metabolism. Our previous work demonstrated that depletion of GSH by culturing cells in tissue culture medium lacking the amino acids cysteine and meth...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Voehringer, D. W., McConkey, D. J., McDonnell, T. J., Brisbay, S., Meyn, R. E.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19676/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9501197/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.6.2956
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