Bax, but not Bcl-x(L), decreases the lifetime of planar phospholipid bilayer membranes at subnanomolar concentrations

Release of proteins through the outer mitochondrial membrane can be a critical step in apoptosis, and the localization of apoptosis-regulating Bcl-2 family members there suggests they control this process. We used planar phospholipid membranes to test the effect of full-length Bax and Bcl-x(L) synth...

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Bibliografiska uppgifter
Huvudupphovsmän: Basañez, G., Nechushtan, A., Drozhinin, O., Chanturiya, A., Choe, E., Tutt, S., Wood, K. A., Hsu, Y.-T., Zimmerberg, J., Youle, R. J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 1999
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC21887/
https://ncbi.nlm.nih.gov/pubmed/10318911
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