Bax, but not Bcl-x(L), decreases the lifetime of planar phospholipid bilayer membranes at subnanomolar concentrations

Release of proteins through the outer mitochondrial membrane can be a critical step in apoptosis, and the localization of apoptosis-regulating Bcl-2 family members there suggests they control this process. We used planar phospholipid membranes to test the effect of full-length Bax and Bcl-x(L) synth...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Basañez, G., Nechushtan, A., Drozhinin, O., Chanturiya, A., Choe, E., Tutt, S., Wood, K. A., Hsu, Y.-T., Zimmerberg, J., Youle, R. J.
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1999
Fag:	Biological Sciences
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21887/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10318911/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.10.5492
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